Adiponectin receptor

Cell surface receptors for adiponectin

The adiponectin receptors (AdipoRs) include the following two receptors, which are bound and activated by adiponectin:

  • Adiponectin receptor 1 (AdipoR1, PAQR1)
  • Adiponectin receptor 2 (AdipoR2, PAQR2)

They are members of the progestin and adipoQ receptor (PAQR) family.[1]

In 2016, the University of Tokyo announced that it would launch an investigation into claims of fabrication of AdipoR1 and AdipoR2 identification data, as accused by an anonymous person/group called Ordinary_researchers.[2]

References

  1. ^ Tang, Y. Tom; Hu, Tianhua; Arterburn, Matthew; Boyle, Bryan; Bright, Jessica M.; Emtage, Peter C.; Funk, Walter D. (2005). "PAQR Proteins: A Novel Membrane Receptor Family Defined by an Ancient7-Transmembrane Pass Motif". Journal of Molecular Evolution. 61 (3): 372–380. Bibcode:2005JMolE..61..372T. doi:10.1007/s00239-004-0375-2. ISSN 0022-2844. PMID 16044242. S2CID 31473802.
  2. ^ University of Tokyo to investigate data manipulation charges against six prominent research groups ScienceInsider, Dennis Normile, Sep 20, 2016
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Membrane proteins, receptors: cell surface receptors
G protein–coupled receptor
Class A
  • Eicosanoid receptor (Prostaglandin receptor)
  • Protease-activated receptor
  • Neurotransmitter receptor
  • Purinergic receptor
  • Biogenic amine receptor
  • Olfactory receptor
Class B
  • Secretin receptor
Class C
  • Metabotropic glutamate receptor
Class D
  • Pheromone receptor
Class E
  • cAMP receptor
Class F
Ligand-gated ion channelEnzyme-linked receptorOther/ungrouped


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